Quetiapine Fumarate eq. To Quetiapine – 25 mg

Brand Name : RESTOPIN – 25

Composition : Quetiapine Fumarate eq. To Quetiapine – 25 mg

Packing : ( 10 x 14)

Description : Quetiapine Fumarate eq. Quetiapine – 25 mg, manufactured by Lifegenix and is circulated in the market with the brand name of RESTOPIN 25. It is a low-dose atypical antipsychotic medication containing Quetiapine, which is used to manage mental health conditions such as schizophrenia, bipolar disorder, and, in some cases, adjunctive treatment for major depressive disorder (MDD). At 25 mg, this is often the starting or low-dose formulation, suitable for dose titration or for managing milder symptoms such as anxiety or insomnia under medical supervision.

Mechanism Of Action

Quetiapine Fumarate belongs to a class of drugs known as atypical antipsychotics. The Quetiapine Fumarate modulates the neurotransmitters, which are mostly Dopamine and serotonin in the brain. Acting on these chemical messengers helps in keeping the balance of mood, reduces hallucinations or delusions, improves concentration and sleep, and promotes emotional stability.

Usages and Benefits of Quetiapine Fumarate Eq. To Quetiapine

• Schizophrenia – to reduce symptoms such as hallucinations, delusions, and disorganized thinking
• Bipolar disorder – both manic and depressive episodes
• Adjunct treatment in Major Depressive Disorder (MDD)
• Sleep and anxiety disorders – off-label use in low doses (such as 25 mg) for short-term relief in carefully monitored cases
• Note: RESTOPIN 25 is not a sleep aid or anxiety medication but may be used off-label under the guidance of a psychiatrist.

Dosages and Administration 

• It is typically initiated at 25mg and is taken once or twice a day according to the conditions.

• Dosages can be increased gradually based on the patient’s response and tolerability.

• Should be taken orally, with or without food.

• Always follow the physician's prescribed schedule.

Side Effects of Quetiapine Fumarate eq. To Quetiapine

Like all medications, RESTOPIN 25 may cause side effects in some individuals. Common side effects include:

• Drowsiness or sedation

• Dizziness

• Dry mouth

• Constipation

• Weight gain

• Headache

• Orthostatic hypotension (drop in blood pressure when standing)

Serious but rare side effects may include:

• Extrapyramidal symptoms (e.g., tremors, rigidity)

• Metabolic changes (like elevated blood sugar or cholesterol)

• Tardive dyskinesia (involuntary facial movements)

• Neuroleptic Malignant Syndrome (a medical emergency)

If any serious side effects occur, medical attention should be sought immediately.

Precautions

• Not recommended in elderly patients with dementia-related psychosis due to an increased risk of death.

• Should be used with caution in patients with cardiovascular disease, liver impairment, or a history of seizures.

• Alcohol and other CNS depressants should be avoided while taking this medication.

• Regular monitoring of weight, blood sugar, and lipid profile may be advised during prolonged use.

Restopin 25 is a reliable and widely used atypical antipsychotic that provides the foundational treatment option for various psychiatric conditions. The low-dose formula allows flexibility in treatment planning, especially for new patients or those requiring a gradual titration.
It is strongly recommended that it be used under medical supervision due to its potential side effects and the importance of individualized dosing.

Storage Instructions

• Store at room temperature (below 25°C).

• Keep in a cool, dry place, away from direct sunlight and moisture.

• Keep out of reach of children.