Sitagliptin 50 mg & Metformin 500 mg

Brand Name : SITAGIX M 500

Composition : Sitagliptin 50 mg & Metformin 500 mg

Packing : 10x10

Description :

It is a combination drug that includes two medicines: Sitagliptin and Metformin, used to control high blood sugar levels in individuals suffering from type 2 diabetes mellitus (Antidiabetics).Sitagliptin helps your pancreas produce more insulin and reduces the excess sugar made by the liver. Lowering the blood glucose levels is an essential part of controlling diabetes. Metformin lowers glucose production in the liver, which delays glucose absorption. For optimal results, take it at the same time each day, while maintaining a balanced diet and exercising regularly.
Lifegenix is a well-renowned PCD Pharma Franchise Company. Known for their wide range of ISO, WHO-certified pharmaceutical products. Sitagliptin and Metformin are offered under the brand name SITAGIX M 500. It signals the liver to stop producing sugar when the level of glucose exceeds in the blood. Keep checking your blood glucose levels while using medication. It is ineffective for individuals having type 1 diabetes. 

Mode of Action for Sitagliptin and Metformin HCL Tablets 

It's a combination of 2 medicines that work together to lower the blood glucose level. Sitagliptin inhibits the enzyme DPP-4, which increases insulin secretion from pancreatic beta cells and decreases glucagon secretion from pancreatic alpha cells, which reduces liver glucose production and lowers postprandial and fasting blood glucose levels. On the other hand,  Metformin is a biguanide, which lowers glucose production in the liver, delays glucose absorption from the intestines, and increases the body's sensitivity to insulin. Both complement each other’s mechanisms and offer better glycemic control than either drug alone.

Medical Benefits of Sitagliptin and Metformin HCLTablets 

It's a widely prescribed combination therapy used to manage the blood glucose level for individuals suffering from type 2 diabetes mellitus. A list of key benefits has been mentioned below as follows: 

1 . Sitagliptin and metformin play a significant role in controlling blood sugar levels and preventing serious complications of diabetes, such as eye damage, kidney damage, nerve damage, and loss of limb. 
2. It helps in improving overall glycemic control by enhancing insulin sensitivity and decreasing hepatic glucose production.
3. Sitagliptin and metformin are weight-neutral, decreasing the chances of weight gain, unlike other diabetes medicines.
4.  Also reduces the risk of major cardiovascular events such as heart attacks and strokes. 

Side Effects of Sitagliptin and Metformin HCL Tablets
Most of the side effects do not require any medical attention; if they persist and cause any discomfort, consult your healthcare provider. A list of the following side effects has been mentioned below:

1. Diarrhea
2. Upper respiratory tract infection
3. Headache 
4. Low blood sugar
5. Sore throat
6. Nausea
7. Stomach upset
8. Indigestion
9. Fatigue 
10. Fast heartbeat

General Safety and Precautions
A list of safety precautions must be followed before taking Sitagliptin and Metformin Tablets. Disclose your current or past health conditions to your doctor to avoid any adverse side effects.

1. Avoid taking metformin and sitagliptin if you have severe kidney disease or metabolic acidosis.
2. Take it with food to lower your chance of having an upset stomach.
3. Monitor your blood sugar level regularly while you are taking this medicine.
4. Avoid consumption of alcohol while on treatment with sitagliptin+metformin.
5. Consult your doctor before taking the medication during pregnancy. 
6. Inform your healthcare provider if you experience any deep or rapid breathing, persistent nausea, vomiting, it's due to an excess of lactic acid in the blood, termed as lactic acidosis. 

 Frequently Asked Questions 
1. What are Sitagliptin and Metformin Tablets used for?
Sitagliptin and Metformin are used together to help control blood sugar levels in people with type 2 diabetes. They work in different ways to lower blood sugar and help manage the condition better.

2. How do Sitagliptin and Metformin Tablets work?
Metformin reduces the sugar made by your liver and helps your body use insulin better. Sitagliptin increases insulin release and lowers sugar levels after meals. Together, they help control blood sugar more effectively.

3. When should I take Sitagliptin and Metformin Tablets ?
It’s usually taken once or twice daily with meals to reduce stomach upset. Always follow your doctor’s instructions on how and when to take the medication.

 4. Do I still need to diet and exercise while taking this medication?
Yes, healthy eating and regular exercise are important. The medicine works best when combined with a balanced diet and an active lifestyle.